Dr. Mikhail Kosiborod, MD- Dapagliflozin in PRESERVED Ejection Fraction Heart Failure (PRESERVED-HF) @MkosiborodMD @S...

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Dapagliflozin in PRESERVED Ejection Fraction Heart Failure (PRESERVED-HF)

https://clinicaltrials.gov/ct2/show/NCT03030235?recrs=e&cond=Heart&phase=23&lupd_s=06%2F01%2F2021&lupd_e=01%2F18%2F2022&draw=2&rank=4

The major goal of this study is to see how dapagliflozin affects heart failure, disease-specific biomarkers, symptoms, health status, and quality of life in patients with chronic heart failure with retained systolic function when compared to placebo.

Description in detail:

The impact of once-daily dapagliflozin 10 mg on heart failure disease-specific biomarkers (NTproBNP and BNP), symptoms, health status, and quality of life in patients with chronic heart failure with maintained systolic function in a 12-week randomized, double-blind, placebo-controlled trial. The effects of dapagliflozin vs. placebo on various echocardiographic parameters will also be investigated in an imaging substudy.