Dr. Kim Eagle provides a weekly tip for clinicians on the front lines of the COVID-19 pandemic. This week's tip focuses on three large randomized trial outcomes for lopinavir-ritonavir (https://www.acc.org/latest-in-cardiol...), dexamethasone (https://www.acc.org/latest-in-cardiol...), and remdesivir (https://www.acc.org/latest-in-cardiol...) and their possible effectiveness to reduce mortality in patients hospitalized with COVID-19.